In many malignancies—including breast, lung, prostate, and gastrointestinal cancers—miR-140 is significantly downregulated. It typically acts as a tumor suppressor by inhibiting cell proliferation, invasion, and metastasis while encouraging cell death (apoptosis).
If you are researching this for a specific project, let me know: 140 РђРЅРѕРЅСЃ
Because its levels fluctuate heavily depending on the presence of tumors, tracking miR-140 expression quantities in tissue is actively researched as a way to predict clinical outcomes and survival rates in patients with neoplasia. In many malignancies—including breast
It is necessary for normal endochondral ossification, the process by which the growing skeleton is formed. Mice lacking this gene often exhibit dwarfism and craniofacial abnormalities due to impaired chondrocyte proliferation. 140 РђРЅРѕРЅСЃ