The Giants prioritized college experience, selecting nine college players in their first 10 picks to address a perceived lack of arms in their farm system. Mississippi State Matt Mikulski Mason Black Eric Silva JSerra Catholic HS (CA) Rohan Handa Seth Lonsway Ohio State Nick Sinacola Ian Villers California Mat Olsen Central Arizona College Vaun Brown Florida Southern Notable Performance & Development Marco Luciano
The used their 2021 MLB Draft to aggressively bolster their pitching depth, selecting 14 pitchers out of 20 total picks. The class was headlined by first-round pick Will Bednar , a right-hander from Mississippi State who had just earned College World Series Most Outstanding Player honors. 2021 San Francisco Giants Draft Class Summary Giants (2021)