Sgk1 4 Zip (1080p • HD)

SGK1 acts as a "hub" molecule regulating diverse cellular processes:

: Gene variants conferring increased SGK1 activity are associated with salt-sensitive hypertension and obesity. SGK1 4 zip

: It is a "stress-response" gene, rapidly up-regulated by serum, glucocorticoids, mineralocorticoids, and various cell stressors like ischemia and osmotic changes. Biological Roles & Physiological Impact SGK1 acts as a "hub" molecule regulating diverse

: It inhibits apoptosis by phosphorylating and inactivating pro-apoptotic factors like FOXO3a and p53 . rapidly up-regulated by serum