For most modern Ford F-250s, the short answer is or Mercon V , but the exact type depends entirely on your truck's model year and engine .
Note: Some 2023+ models may require Mercon ULV; check your dipstick. Use Mercon LV . Ford superseded Mercon SP with LV for these years. 1997 – 2002 (4R100 Transmission): Use Mercon V .
Look for the "TR" code on the driver’s side door jamb sticker to identify your specific transmission model.
To give you the most accurate capacity and part number, could you tell me: What is the of your F-250?
Which does it have (e.g., 6.2L Gas, 6.7L PowerStroke)? Are you doing a simple drain or a full system flush ?
Check the "Capacities and Specifications" section in the back of your manual.